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Over the course of twenty years, the biotechnological and pharmaceutical company Novartis has succeeded in transforming the industrial estate of its preceding companies into a modern and open campus. An urban grid based on a master plan by Vittorio Magnago Lampugnani emerged to the north of Basel, where successive open spaces as well as world-ranking buildings and artworks have found a place. Since autumn 2022, the campus has also been freely accessible to the public on work days. The Novartis Campus Guide is the first publication devoted to the company’s global headquarters. It serves both as a chronological review and a thematic guide.